0.05% Cream (Retin-A equivalent)


ReFissa is prescribed by dermatologists to:

  • Diminish fine facial wrinkles
  • Fade irregular pigmentation due to sun damage
  • Smooth your skin so it's softer to the touch (tactile roughness)
  • ReFissa is different because:

It's available by prescription only
It's clinically proven to be effective and it's approved by the FDA
It's the only 0.05%-strong prescription tretinoin cream that's fragrance-free with a moisturizing, emollient base

How It Works

  • Contains tretinoin, a prescription-strength form of vitamin A
  • Works deep at the skin's cellular level5
  • Increases collagen, which the body produces less of with age6
  • Is approved by the FDA for fine facial wrinkles, irregular pigmentation and rough skin

In a clinical trial, 71% of women saw improvement in their fine facial wrinkles and 83% saw improvement in irregular pigmentation.